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suggestion :

Try use system recovery to recover pc to before you open the problem file

if still fail then :

RUN anti-virus scanning

1.  reboot and enter BIOS mode > set 1st boot device to cdrom

2.  or download and burn cd from www.bitdefender.com
     bitdefender_2008_RescueCD_v2.iso

     use it  to boot up pc  and run virus scanning

3.  put windows cd into cdrom > reboot

    after bootup from windows > select repair to repair windows